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Biorevitalization Explained
The Science of Skin Rejuvenation
What is Facial Biorevitalization?

Biorevitalization is a cosmetic procedure that involves multiple intradermal injections of hyaluronic acid-based preparations.
Hyaluronic acid retains water, stimulates collagen production, and participates in regeneration, thereby directly influencing the skin's elasticity, turgor, and freshness. With age, the amount of hyaluronic acid in the epidermis decreases. External administration of the preparation is necessary to compensate for this deficiency, making the skin more toned and elastic, improving complexion, and smoothing fine wrinkles.
Another important property of hyaluronic acid is that it provides a connection between cells, allowing some cells to satisfy their needs using the resources of others. A high content of hyaluronic acid in the extracellular fluid is important for tissue hydrodynamics, cell migration, and division processes. Additionally, hyaluronic acid stabilizes blood vessel walls and participates in angiogenesis, which is the formation of new blood vessels.
It's important to distinguish biorevitalization from other aesthetic cosmetology methods: hyaluronic acid filler injections and mesotherapy.
Fillers are high-density preparations used to "fill" expression lines. Mesotherapy involves intradermal injection of a whole cocktail of preparations: vitamins, peptides, lipolytics, and amino acids. Hyaluronic acid can be one of many components in mesotherapy, but not the only or main one.

Biorevitalization, on the other hand, involves injecting only low-density hyaluronic acid.
Mesotherapy is more suitable for young skin that doesn't require intense hydration. Mesococktails help maintain excellent skin condition, saturating it with vitamins and other beneficial ingredients.

For ageing skin—after 35, and in some cases even after 30—biorevitalisation is preferable. Biorevitalizants, the preparations used for biorevitalisation, contain a higher percentage of hyaluronic acid and longer chains, thus providing a more powerful moisturising effect.
Depending on the type of biorevitalization, after the procedure, there may be needle marks, redness, small bruises, and swelling on the skin. These phenomena usually disappear after a few days.
Types of Facial Biorevitalization

There is no strict classification as this procedure is more aesthetic than medical, and cosmetologists continually offer new biorevitalization options. They primarily differ only in the method of drug administration.

Injection Biorevitalization

This includes any variations of the procedure involving injections. For example, the traditional method where the drug is injected with a syringe and a short, thin needle. Or the use of special devices with interchangeable cartridges that allow for a dozen injections at once. This type of biorevitalization is also called fractional.

Non-Injection Biorevitalization

This comes in various forms, such as laser or oxygen biorevitalization. In the first case, the drug is delivered to the skin with a laser, and in the second, with a thin stream of oxygen under slight pressure. This is supposed to help avoid the side effects of injections—swelling, redness, and pain.

Methods such as transporting hyaluronic acid with a laser or electric current (iontophoresis) have significant drawbacks. They result in a much less pronounced and shorter-lasting effect and the inability to deliver therapeutic components to the deep layers of the skin, so they are rarely used.
How Effective Is Facial Biorevitalization?

The procedure is relatively new, and large-scale studies with representative samples on this topic have not yet been conducted. Moreover, even researchers periodically confuse biorevitalization with mesotherapy.

Nevertheless, there are several studies that show the procedure effectively copes with its tasks—it increases skin elasticity and turgor, improves complexion, and reduces the number of fine wrinkles.

To achieve the desired aesthetic result, 3-5 procedures are required with an interval of 14-30 days. The effect is cumulative and lasts 2-4 months.

Modern biorevitalization preparations are conditionally divided into two groups: classic and prolonged-action. They differ in composition and injection technique. Biorevitalizants of the first group can be injected both superficially and into the deep layers of the skin.

Prolonged-action preparations have a more complex formula, which allows for a slower breakdown of hyaluronic acid. They are injected only into the deep layers of the skin, with a frequency of one procedure every six months.

The selection of the drug is up to the doctor. Depending on the condition of the skin and the presence of problems, the cosmetologist will select the appropriate drug and develop an individual treatment plan.
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